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Individual nano objects, at high speed,
by biological or specific criteria
A key issue for several health areas
Fast detection and sorting of nano sized objects is now possible with Hekat’s technology. Our goal is to become the first worldwide company to offer a microfluidic and optical instrument that can detect, count and sort individual biological nano objects, by functional critera.
QUALITY CONTROL
Viral Vector Engineering
and Manufacturing
CANCER DIAGNOSIS
Improving prognosis
with exosomes
ENVIRONMENT
Water quality control
NANOPARTICLES
SYNTHESIS
Process control
for viral vectors engineering and manufacturing
Viral vectors have many medical applications
Gene therapy, Immunotherapy (CarT cells) for cancer treatment, vaccines, etc… To produce higher volumes, challenges throughout the manufacturing process must be solved, in particular quality control and yield.
Gene Therapy
Immuniotherapy
(carT cells)
RNA vaccines
Gene modification
Regenerative medicine
Bioproduction quality control
The proportion between full and empty viral capsids is a key indicator during development and production of viral vecors. Current immunologic testing are very time consuming, and give highly variable results (upto a factor of five depending on the CRO). Hence vectors are produced « blinfolded ».
Hekat’s solution can measure this ratio within minutes.
The next revolution in medicine
The exosome revolution may well be the greatest advance in physiology and medecine since antibiotics
Exosomes, a Clinical Compendium – Collectif 2019 – Academic Press
Extracellular vesicles
typically 30-100 nm in diameter,
generated by cells
involved in intercellular communication
Present in very large numbers
in our bodily fluids.
Booming sector
thanks to prognostic, diagnostic, and therapeutic applications
The Hekat solution :
Sorting exosomes by functional criteria, such as the type of cell they originate from
95% of cases are fatal
Biopsy : invasive and hazardous
Liquid biopsy : sensitivity issues
Very late diagnosis, standard and untargeted therapy
Analyse the exosomes originated from the tumor, without requiring invasive and hazardous biopsy
Early diagnosis
Tailored treatment
Improved prognosis
Helthcare costs reduction
a key experience
